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Create post-transcriptionally
5′-capped and 3′-poly(A) tailed mRNA with greatly reduced dsRNA content to lower innate immunogenicity.

mRNA transcription using canonical or modified nucleotides.

Easy and scalable enzymatic double-stranded RNA removal from IVT RNA samples.

Ideal for in-process or final product testing to measure mRNA
5’-capping efficiency or 3’-poly(A) tail length from
20-300+ A’s.