Complete mRNA Synthesis
Create post-transcriptionally
5′-capped and 3′-poly(A) tailed mRNA with greatly reduced dsRNA content to lower innate immunogenicity.
In Vitro Transcription
mRNA transcription using canonical or modified nucleotides.
5' Capping
Post-transcriptional addition of Cap 0 or
Cap 1 with ~100% efficiency.
3'-Poly(A) Tailing
Post-transcriptional tailing of mRNAs to lengths of 20-300+ A’s.
dsRNA Removal
Easy and scalable enzymatic double-stranded RNA removal from IVT RNA samples.
mRNA Quality Control
Ideal for in-process or final product testing to measure mRNA
5’-capping efficiency or 3’-poly(A) tail length from
20-300+ A’s.
CELLSCRIPT™ products used in high impact journals
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Need help designing your mRNA synthesis workflow to ensure lowest immunogenicity?
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