Publications
CELLSCRIPT™ products used in high impact journals
- mRNA-engineered mesenchymal stem cells for targeted delivery of interleukin-10 to sites of inflammation
- Enhanced homology-directed repair for highly efficient gene editing in hematopoietic stem/progenitor cells
- CRISPR-targeted MAGT1 insertion restores XMEN patient hematopoietic stem cells and lymphocytes
- Extended Detection in Peripheral Blood Following Infusion of Chronic Granulomatous Disease HSPCs
- Multiplexed cytokine and antigen mRNA administration generates durable anti-tumor immunity against pancreatic cancer
- Expression of nano-engineered RNA organelles in bacteria
- Position-specific ORF nucleoside-ribose modifications enabled by complete chemical synthesis enhance mRNA stability and translation
- Proton channels govern vesicular carbonate chemistry in mineralizing cells of a marine calcifier
- A rich conformational palette underlies human CaV2.1-channel availability
- RagD auto-activating mutations impair MiT/TFE activity in kidney tubulopathy and cardiomyopathy syndrome
- Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics
- Plug-and-play protein biosensors using aptamer-regulated in vitro transcription
- dCas13-mediated translational repression for accurate gene silencing in mammalian cells
- DMDA-PatA mediates RNA sequence-selective translation repression by anchoring eIF4A and DDX3 to GNG motifs
- Calibrated ribosome profiling assesses the dynamics of ribosomal flux on transcripts (PMC)
- Combinatorial optimization of mRNA structure, stability, and translation (PMC)
- G-quadruplex topologies determine the functional outcome of guanine-rich bioactive oligonucleotides
- mRNA turnover dynamics are affected by cell differentiation and loss of the cytosine methyltransferase Nsun2
- Versatile strategy using vaccinia virus-capping enzyme to synthesize functional 5′ cap-modified mRNAs
- High resolution biosensor to test the capping level and integrity of mRNAs
- The complete pathway for co-transcriptional mRNA maturation within a large protein of a non-segmented negative-strand RNA virus
- Synthetic circuit for exact adaptation and fold-change detection
