Cap-Clip™ Acid Pyrophosphatase
- Remove 5’ cap structures (decapping) from various RNAs, including mRNA.
- Substitute unit-for-unit in any preexisting protocol using Tobacco Acid Pyrophosphatase (TAP).
Product is for research use only (RUO)
Product Description:
Cap-Clip™ Acid Pyrophosphatase is a plant-derived enzyme that hydrolyzes various pyrophosphate bonds, including the pyrophosphate bonds of the 5' cap of eukaryotic mRNAs, small nuclear RNAs (snRNAs), heterogeneous nuclear RNAs (hnRNAs) and some viral RNAs. Complete decapping generates RNA that has a
5'-monophosphate group.
Cap-Clip™ Acid Pyrophosphatase was developed as an improvement over Tobacco Acid Pyrophosphatase (TAP). It can be used unit-for-unit in any previously developed protocol that utilized TAP and has an identical reaction buffer. With lot-to-lot consistency, absence of critical contaminants and a dependable inventory, Cap-Clip™ Acid Pyrophosphatase is a superior replacement for all TAP needs.
